ICP-MS Analysis Laboratories
Inductively coupled plasma mass spectrometry measures elements at trace and ultra-trace levels after the sample is digested or extracted into solution.
What does it measure?
- Trace element concentrations
- Elemental impurities in drug products and excipients
- Metals in water, soil and extracts
- Isotopic information where required
When is it used?
- Elemental impurity assessment
- Environmental metals analysis
- High-purity material qualification
- Extractables and leachables metals screening
Sample considerations
- Containers must be selected and cleaned to avoid metal contamination.
- Digestion approach depends on the matrix; state the matrix clearly.
Laboratories with relevant capabilities
- NSL Analytical Services (Cleveland, OH) — Chemical Analysis, Elemental Analysis, Metallurgical Analysis
- BA Sciences (Salem, NH) — Microbiology, Sterility Testing, Chemical Analysis
- Laboratory Testing Inc. (Hatfield, PA) — Materials Testing, Mechanical Testing, Chemical Analysis
- NAMSA (Northwood, OH) — Biocompatibility, Chemical Analysis, Extractables & Leachables
Frequently asked questions
- When is ICP-MS chosen over ICP-OES?
- ICP-MS generally reaches lower detection limits, so it is used when trace or ultra-trace levels matter. ICP-OES is often sufficient for higher concentrations.
Confirm standard edition, jurisdiction and actual laboratory scope. Service references are not partnerships or endorsements.