Medical Device Packaging & Sterile Barrier Testing Laboratories

Medical device packaging must keep the device sterile until use. ISO 11607 sets requirements for sterile barrier systems; laboratories support it with seal strength (ASTM F88), integrity tests such as dye penetration and bubble leak, accelerated aging (ASTM F1980) alongside real-time aging, and distribution simulation (ASTM D4169 or ISTA procedures).

What does it measure?

  • Seal strength
  • Package integrity (leak detection)
  • Performance after accelerated and real-time aging
  • Performance after distribution simulation
  • Temperature and humidity conditioning effects

When is it used?

  • Qualifying a new sterile barrier system
  • Supporting a labelled shelf life
  • Material, sealer or supplier changes
  • Investigating seal or package failures

Sample considerations

  • Use packages sealed at validated process limits, including worst-case settings.
  • Plan real-time aging in parallel with accelerated aging.

Laboratories with relevant capabilities

  • Intertek (Lake Forest, CA) — Materials Testing, Metallurgical Analysis, Chemical Analysis
  • Keystone Compliance (New Castle, PA) — Electrical & EMC, Wireless & RF, Environmental Testing
  • Bureau Veritas Consumer Products Services (Buffalo, NY) — Chemical Analysis, Mechanical Testing, Microbiology
  • Perritt Laboratories (Hightstown, NJ) — Package Testing, Microbiology Testing
  • Impact Solutions (Livingston, Scotland) — Plastics Testing, Polymer Testing, Materials Testing
  • Tri-Wall UK (Monmouth, Wales) — Package Testing, Transit Testing, Dangerous Goods Packaging Testing

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